Abstract Background Hepatocyte transplantation has been proposed as an effective treatment for patients with acute liver failure (ALF), but its application is limited by a severe Industrial Vacuum Accessory shortage of donor livers.Human pluripotent stem cells (hPSCs) have emerged as a potential cell source for regenerative medicine.Human amniotic
Regional, racial, gender, and tumor biology disparities in breast cancer survival rates in Africa: A systematic review and meta-analysis.
BackgroundThe survival rates from breast cancer in Africa are poor and yet the incidence rates are on the rise.In this study, we hypothesized that, in Africa, a continent with great disparities in socio-economic status, race, tumor biology, and cultural characteristics, the survival rates from breast cancer vary greatly based on region, tumor biolo
Determination of the starting dose in the first-in-human clinical trials with monoclonal antibodies: a systematic review of papers published between 1990 and 2013
Hoon Young Suh,1 Carl C Peck,2 Kyung-Sang Yu,1 Howard Lee1,3 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, Seoul National Hand Wash University Hospital, Seoul, Korea; 2Department of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California, San Francisco, CA, USA; 3Department of Transdiscipl
Aspirin-free antithrombotic management following coronary stenting. Myth or reality?
ABSTRACT The use of aspirin in combination with a P2Y12 receptor inhibitor, also known as dual antiplatelet therapy, is at the cornerstone of treatment for patients undergoing coronary stenting.The use of newer generation P2Y12 inhibitors (ie, prasugrel and ticagrelor), characterized by Color depositing conditioner more potent antiplatelet effects